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Perilymph Pharmacokinetics of Markers and Dexamethasone Applied and Sampled at the Lateral Semi-Circular Canal

Perilymph pharmacokinetics was investigated by a novel approach, in which solutions containing drug or marker were injected from a pipette sealed into the perilymphatic space of the lateral semi-circular canal (LSCC). The cochlear aqueduct provides the outlet for fluid flow so this procedure allows...

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Bibliographic Details
Main Authors: Salt, Alec N., Hartsock, Jared J., Gill, Ruth M., Piu, Fabrice, Plontke, Stefan K.
Format: Artigo
Language:Inglês
Published: Springer-Verlag 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3505589/
https://ncbi.nlm.nih.gov/pubmed/22968908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10162-012-0347-y
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