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Perilymph pharmacokinetics of locally-applied gentamicin in the guinea pig

Intratympanic gentamicin therapy is widely used clinically to suppress the vestibular symptoms of Meniere’s disease. Dosing in humans was empirically established and we still know remarkably little about where gentamicin enters the inner ear, where it reaches in the inner ear and what time course it...

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Bibliografische gegevens
Gepubliceerd in:Hear Res
Hoofdauteurs: Salt, AN, Hartsock, JJ, Gill, RM, King, E, Kraus, FB, Plontke, SK
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5121026/
https://ncbi.nlm.nih.gov/pubmed/27725177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heares.2016.10.003
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