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Perilymph pharmacokinetics of locally-applied gentamicin in the guinea pig

Intratympanic gentamicin therapy is widely used clinically to suppress the vestibular symptoms of Meniere’s disease. Dosing in humans was empirically established and we still know remarkably little about where gentamicin enters the inner ear, where it reaches in the inner ear and what time course it...

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Détails bibliographiques
Publié dans:Hear Res
Auteurs principaux: Salt, AN, Hartsock, JJ, Gill, RM, King, E, Kraus, FB, Plontke, SK
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5121026/
https://ncbi.nlm.nih.gov/pubmed/27725177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heares.2016.10.003
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