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Toxic amyloid-β oligomers induced self-replication in astrocytes triggering neuronal injury

BACKGROUND: Soluble amyloid-β oligomer (AβO) induced deleterious cascades have recently been considered to be the initiating pathologic agents of Alzheimer's disease (AD). However, little is known about the neurotoxicity and production of different AβOs. Understanding the production and spread...

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Dettagli Bibliografici
Pubblicato in:EBioMedicine
Autori principali: Wang, Wei, Hou, Ting-ting, Jia, Long-fei, Wu, Qiao-qi, Quan, Mei-na, Jia, Jian-ping
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491655/
https://ncbi.nlm.nih.gov/pubmed/30926423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.03.049
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