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Toxic amyloid-β oligomers induced self-replication in astrocytes triggering neuronal injury

BACKGROUND: Soluble amyloid-β oligomer (AβO) induced deleterious cascades have recently been considered to be the initiating pathologic agents of Alzheimer's disease (AD). However, little is known about the neurotoxicity and production of different AβOs. Understanding the production and spread...

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Dades bibliogràfiques
Publicat a:EBioMedicine
Autors principals: Wang, Wei, Hou, Ting-ting, Jia, Long-fei, Wu, Qiao-qi, Quan, Mei-na, Jia, Jian-ping
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491655/
https://ncbi.nlm.nih.gov/pubmed/30926423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.03.049
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