Toxic amyloid-β oligomers induced self-replication in astrocytes triggering neuronal injury

BACKGROUND: Soluble amyloid-β oligomer (AβO) induced deleterious cascades have recently been considered to be the initiating pathologic agents of Alzheimer's disease (AD). However, little is known about the neurotoxicity and production of different AβOs. Understanding the production and spread...

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Enregistré dans:
Détails bibliographiques
Publié dans:EBioMedicine
Auteurs principaux: Wang, Wei, Hou, Ting-ting, Jia, Long-fei, Wu, Qiao-qi, Quan, Mei-na, Jia, Jian-ping
Format: Artigo
Langue:Inglês
Publié: Elsevier 2019
Sujets:
Research paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491655/
https://ncbi.nlm.nih.gov/pubmed/30926423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.03.049
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