Toxic amyloid-β oligomers induced self-replication in astrocytes triggering neuronal injury

BACKGROUND: Soluble amyloid-β oligomer (AβO) induced deleterious cascades have recently been considered to be the initiating pathologic agents of Alzheimer's disease (AD). However, little is known about the neurotoxicity and production of different AβOs. Understanding the production and spread...

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Bibliographische Detailangaben
Veröffentlicht in:EBioMedicine
Hauptverfasser: Wang, Wei, Hou, Ting-ting, Jia, Long-fei, Wu, Qiao-qi, Quan, Mei-na, Jia, Jian-ping
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2019
Schlagworte:
Research paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491655/
https://ncbi.nlm.nih.gov/pubmed/30926423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.03.049
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