Methylglyoxal-Derived Advanced Glycation Endproducts Accumulate in Multiple Sclerosis Lesions

Multiple sclerosis (MS) is a demyelinating autoimmune disease in which innate and adaptive immune cells infiltrate the central nervous system (CNS) and damage the myelin sheaths surrounding the axons. Upon activation, infiltrated macrophages, CNS-resident microglia, and astrocytes switch their metab...

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Опубликовано в: :Front Immunol
Главные авторы: Wetzels, Suzan, Vanmierlo, Tim, Scheijen, Jean L. J. M., van Horssen, Jack, Amor, Sandra, Somers, Veerle, Schalkwijk, Casper G., Hendriks, Jerome J. A., Wouters, Kristiaan
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2019
Предметы:
Immunology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491451/
https://ncbi.nlm.nih.gov/pubmed/31068938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00855
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