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Advanced Glycation Endproducts Are Increased in the Animal Model of Multiple Sclerosis but Cannot Be Reduced by Pyridoxamine Treatment or Glyoxalase 1 Overexpression

Multiple sclerosis (MS) is a demyelinating autoimmune disease of the central nervous system (CNS). The immune response in MS patients leads to the infiltration of immune cells in the CNS and their subsequent activation. Immune cell activation induces a switch towards glycolysis. During glycolysis, t...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Wetzels, Suzan, Wouters, Kristiaan, Miyata, Toshio, Scheijen, Jean L. J. M., Hendriks, Jerome J. A., Schalkwijk, Casper G., Vanmierlo, Tim
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983766/
https://ncbi.nlm.nih.gov/pubmed/29702605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19051311
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