Cell-type specific responses to interleukin-1 control microbial invasion and tumor elicited inflammation in colorectal cancer

Chronic inflammation drives the progression of colorectal cancer (CRC). Increased expression of interleukin (IL)-17A is associated with poor prognosis, and IL-17A blockade curbs tumor progression in preclinical models of CRC. Here we examined the impact of IL-1 signaling, a key regulator of the IL-1...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Immunity
Egile Nagusiak: Dmitrieva-Posocco, Oxana, Dzutsev, Amiran, Posocco, David F., Hou, Vivianty, Yuan, Wuxing, Thovarai, Vishal, Mufazalov, Ilgiz A., Gunzer, Matthias, Shilovskiy, Igor P., Khaitov, Musa R., Trinchieri, Giorgio, Waisman, Ari, Grivennikov, Sergei I.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6490968/
https://ncbi.nlm.nih.gov/pubmed/30650375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2018.11.015
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