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Influence of gut microbiome on mucosal immune activation and SHIV viral transmission in naive macaques

It is unknown whether the gut microbiome affects HIV transmission. In our recent SHIV vaccine study, we found that the naïve rhesus macaques from two different sources had significantly different rates of infection against repeated low-dose intrarectal challenge with SHIVSF162P4 virus. Exploring cau...

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Detalhes bibliográficos
Publicado no:Mucosal Immunol
Main Authors: Sui, Yongjun, Dzutsev, Amiran, Venzon, David, Frey, Blake, Thovarai, Vishal, Trinchieri, Giorgio, Berzofsky, Jay A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030500/
https://ncbi.nlm.nih.gov/pubmed/29858581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41385-018-0029-0
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