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Differential T cell homing to colon vs. small intestine is imprinted by local CD11c(+) APCs that determine homing receptors

Mechanisms that imprint T cell homing to the small intestine have been well studied; however, those for homing to the colon are poorly understood. Recently, we found that these are distinct subcompartments of the gut mucosal immune system, which implies differential homing. Here, we show that coloni...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Leukoc Biol
Hauptverfasser: Dzutsev, Amiran, Hogg, Alison, Sui, Yongjun, Solaymani-Mohammadi, Shahram, Yu, Huifeng, Frey, Blake, Wang, Yichuan, Berzofsky, Jay A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Leukocyte Biology 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669635/
https://ncbi.nlm.nih.gov/pubmed/28951425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1A1116-463RR
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