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Early SIV dissemination after intra-rectal SIVmac251 challenge was associated with proliferating virus-susceptible cells in the colorectum

OBJECTIVE: Few studies have examined the eclipse time of SIV/HIV infection via the anal route. We aimed to measure the eclipse time after SIVmac251 intra-rectal inoculation, and to investigate the factor(s) associated with early dissemination. DESIGN: 40 macaques were intra-rectally challenged with...

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Detalhes bibliográficos
Publicado no:J Acquir Immune Defic Syndr
Main Authors: Sui, Yongjun, Lee, Eun Mi, Wang, Yichuan, Hogg, Alison, Frey, Blake, Venzon, David, Pal, Ranajit, Berzofsky, Jay A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767727/
https://ncbi.nlm.nih.gov/pubmed/26545123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000000890
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