An interleukin-23- interleukin-22 axis regulates intestinal microbial homeostasis to protect from diet-induced atherosclerosis

While commensal flora is involved in the regulation of immunity, the interplay between cytokine signaling and microbiota in atherosclerosis remains unknown. We found that interleukin (IL)-23 and its downstream target IL-22 restricted atherosclerosis by repressing pro-atherogenic microbiota. Inactiva...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Fatkhullina, Aliia R., Peshkova, Iuliia O., Dzutsev, Amiran, Aghayev, Turan, McCulloch, John A., Thovarai, Vishal, Badger, Jonathan, Vats, Ravi, Sundd, Prithu, Tang, Hsin-Yao, Kossenkov, Andrew V., Hazen, Stanley L., Trinchieri, Giorgio, Grivennikov, Sergei I., Koltsova, Ekaterina K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6257980/
https://ncbi.nlm.nih.gov/pubmed/30389414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2018.09.011
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