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Cell-type specific responses to interleukin-1 control microbial invasion and tumor elicited inflammation in colorectal cancer
Chronic inflammation drives the progression of colorectal cancer (CRC). Increased expression of interleukin (IL)-17A is associated with poor prognosis, and IL-17A blockade curbs tumor progression in preclinical models of CRC. Here we examined the impact of IL-1 signaling, a key regulator of the IL-1...
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| Publicado no: | Immunity |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6490968/ https://ncbi.nlm.nih.gov/pubmed/30650375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2018.11.015 |
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