Distinct phenotype and function of circulating Vδ1(+) and Vδ2(+) γδT-cells in acute and chronic hepatitis B

Hepatitis B virus (HBV) persists with global and virus-specific T-cell dysfunction, without T-cell based correlates of outcomes. To determine if γδT-cells are altered in HBV infection relative to clinical status, we examined the frequency, phenotype and function of peripheral blood Vδ1(+) and Vδ2(+)...

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Publicado en:PLoS Pathog
Autores principales: Chang, Kyong-Mi, Traum, Daniel, Park, Jang-June, Ho, Suzanne, Ojiro, Keisuke, Wong, David K., Wahed, Abdus S., Terrault, Norah A., Khalili, Mandana, Sterling, Richard K., Janssen, Harry L. A., Shuhart, Margaret C., Lau, Daryl T., Roberts, Lewis R., Johnson, Geoffrey S., Kaplan, David E., Betts, Michael R., Lee, William M., Lok, Anna S. F.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2019
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6490945/
https://ncbi.nlm.nih.gov/pubmed/30998783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007715
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