Distinct phenotype and function of circulating Vδ1(+) and Vδ2(+) γδT-cells in acute and chronic hepatitis B

Hepatitis B virus (HBV) persists with global and virus-specific T-cell dysfunction, without T-cell based correlates of outcomes. To determine if γδT-cells are altered in HBV infection relative to clinical status, we examined the frequency, phenotype and function of peripheral blood Vδ1(+) and Vδ2(+)...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Chang, Kyong-Mi, Traum, Daniel, Park, Jang-June, Ho, Suzanne, Ojiro, Keisuke, Wong, David K., Wahed, Abdus S., Terrault, Norah A., Khalili, Mandana, Sterling, Richard K., Janssen, Harry L. A., Shuhart, Margaret C., Lau, Daryl T., Roberts, Lewis R., Johnson, Geoffrey S., Kaplan, David E., Betts, Michael R., Lee, William M., Lok, Anna S. F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6490945/
https://ncbi.nlm.nih.gov/pubmed/30998783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007715
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