Distinct phenotype and function of circulating Vδ1(+) and Vδ2(+) γδT-cells in acute and chronic hepatitis B

Hepatitis B virus (HBV) persists with global and virus-specific T-cell dysfunction, without T-cell based correlates of outcomes. To determine if γδT-cells are altered in HBV infection relative to clinical status, we examined the frequency, phenotype and function of peripheral blood Vδ1(+) and Vδ2(+)...

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Bibliografiske detaljer
Udgivet i:PLoS Pathog
Main Authors: Chang, Kyong-Mi, Traum, Daniel, Park, Jang-June, Ho, Suzanne, Ojiro, Keisuke, Wong, David K., Wahed, Abdus S., Terrault, Norah A., Khalili, Mandana, Sterling, Richard K., Janssen, Harry L. A., Shuhart, Margaret C., Lau, Daryl T., Roberts, Lewis R., Johnson, Geoffrey S., Kaplan, David E., Betts, Michael R., Lee, William M., Lok, Anna S. F.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6490945/
https://ncbi.nlm.nih.gov/pubmed/30998783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007715
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