CRISPR/Cas9 System for Efficient Genome Editing and Targeting in the Mouse NIH/3T3 Cells

BACKGROUND: The Clustered, Regularly Interspaced, Short Palindromic Repeats (CRIS-PR) and CRISPR-associated protein (Cas) system has been used as a powerful tool for genome engineering. In this study, the application of this system is reported for targeting Rag genes to produce mutant mouse NIH/3T3...

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Veröffentlicht in:Avicenna J Med Biotechnol
Hauptverfasser: Mehravar, Maryam, Shirazi, Abolfazl, Mehrazar, Mohammad Mehdi, Nazari, Mahboobeh, Banan, Mehdi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Avicenna Research Institute 2019
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6490412/
https://ncbi.nlm.nih.gov/pubmed/31057716
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