A proteasome-resistant fragment of NIK mediates oncogenic NF-κB signaling in schwannomas

Schwannomas are common, highly morbid and medically untreatable tumors that can arise in patients with germ line as well as somatic mutations in neurofibromatosis type 2 (NF2). These mutations most commonly result in the loss of function of the NF2-encoded protein, Merlin. Little is known about how...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Hum Mol Genet
Päätekijät: Gehlhausen, Jeffrey R, Hawley, Eric, Wahle, Benjamin Mark, He, Yongzheng, Edwards, Donna, Rhodes, Steven D, Lajiness, Jacquelyn D, Staser, Karl, Chen, Shi, Yang, Xianlin, Yuan, Jin, Li, Xiaohong, Jiang, Li, Smith, Abbi, Bessler, Waylan, Sandusky, George, Stemmer-Rachamimov, Anat, Stuhlmiller, Timothy J, Angus, Steven P, Johnson, Gary L, Nalepa, Grzegorz, Yates, Charles W, Wade Clapp, D, Park, Su-Jung
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2019
Aiheet:
General Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6489415/
https://ncbi.nlm.nih.gov/pubmed/30335132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy361
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