A murine model of neurofibromatosis type 2 that accurately phenocopies human schwannoma formation

Neurofibromatosis type 2 (NF2) is an autosomal dominant genetic disorder resulting from germline mutations in the NF2 gene. Bilateral vestibular schwannomas, tumors on cranial nerve VIII, are pathognomonic for NF2 disease. Furthermore, schwannomas also commonly develop in other cranial nerves, dorsa...

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Publicat a:Hum Mol Genet
Autors principals: Gehlhausen, Jeffrey R., Park, Su-Jung, Hickox, Ann E., Shew, Matthew, Staser, Karl, Rhodes, Steven D., Menon, Keshav, Lajiness, Jacquelyn D., Mwanthi, Muithi, Yang, Xianlin, Yuan, Jin, Territo, Paul, Hutchins, Gary, Nalepa, Grzegorz, Yang, Feng-Chun, Conway, Simon J., Heinz, Michael G., Stemmer-Rachamimov, Anat, Yates, Charles W., Wade Clapp, D.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4262489/
https://ncbi.nlm.nih.gov/pubmed/25113746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu414
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