Inhibition of neddylation modification by MLN4924 sensitizes hepatocellular carcinoma cells to sorafenib

Sorafenib remains the standard care for patients with hepatocellular carcinoma (HCC) even though it has low antitumor efficacy. Protein neddylation is abnormally activated in many types of human cancer. However, whether dysregulation of neddylation is involved in HCC progression and whether targetin...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncol Rep
Egile Nagusiak: Yang, Zelong, Zhang, Jie, Lin, Xiaotong, Wu, Di, Li, Guixi, Zhong, Chunlian, Fang, Lei, Jiang, Peng, Yin, Liangyu, Zhang, Leida, Bie, Ping, Xie, Chuan-Ming
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: D.A. Spandidos 2019
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6489087/
https://ncbi.nlm.nih.gov/pubmed/31002342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2019.7098
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