טוען...
Pronounced antiepileptic activity of the subtype‐selective GABA(A)‐positive allosteric modulator PF‐06372865 in the GAERS absence epilepsy model
AIM: Antiepileptic drugs that modulate GABA have the potential to aggravate or improve the symptoms of absence epilepsy. PF‐06372865 is a positive allosteric modulator (PAM) of α2/3/5 subunit‐containing GABA(A) receptors with minimal activity at α1‐containing receptors, which are believed to mediate...
שמור ב:
| הוצא לאור ב: | CNS Neurosci Ther |
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| Main Authors: | , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
John Wiley and Sons Inc.
2018
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6488884/ https://ncbi.nlm.nih.gov/pubmed/30101518 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.13046 |
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