Development of CXCR4 modulators based on the lead compound RB-108

The CXCR4/CXCL12 axis plays prominent roles in tumor metastasis and inflammation. CXCR4 has been shown to be involved in a variety of inflammation-related diseases. Therefore, CXCR4 is a promising potential target to develop novel anti-inflammatory agents. Taking our previously discovered CXCR4 modu...

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Bibliographic Details
Published in:Eur J Med Chem
Main Authors: Bai, Renren, Jie, Xiaokang, Sun, Jian, Liang, Zhongxing, Yoon, Younghyoun, Feng, Amber, Oum, Yoonhyeun, Yu, Wenyan, Wu, Rui, Sun, Bin, Salgado, Eric, Xie, Yuanyuan, Shim, Hyunsuk
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6488424/
https://ncbi.nlm.nih.gov/pubmed/30981691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2019.03.065
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