Suppression of the gut microbiome ameliorates age‐related arterial dysfunction and oxidative stress in mice

KEY POINTS: Age‐related arterial dysfunction, characterized by oxidative stress‐ and inflammation‐mediated endothelial dysfunction and arterial stiffening, is the primary risk factor for cardiovascular diseases. To investigate whether age‐related changes in the gut microbiome may mediate arterial dy...

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Pubblicato in:J Physiol
Autori principali: Brunt, Vienna E., Gioscia‐Ryan, Rachel A., Richey, James J., Zigler, Melanie C., Cuevas, Lauren M., Gonzalez, Antonio, Vázquez‐Baeza, Yoshiki, Battson, Micah L., Smithson, Andrew T., Gilley, Andrew D., Ackermann, Gail, Neilson, Andrew P., Weir, Tiffany, Davy, Kevin P., Knight, Rob, Seals, Douglas R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
Soggetti:
Cardiovascular
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487935/
https://ncbi.nlm.nih.gov/pubmed/30714619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP277336
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