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Mutant p53 in colon cancer

The accumulation of genetic alterations in driver genes is responsible for the development and malignant progression of colorectal cancer. Comprehensive genome analyses have revealed the driver genes, including APC, KRAS, TGFBR2, and TP53, whose mutations are frequently found in human colorectal can...

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Bibliographic Details
Published in:J Mol Cell Biol
Main Authors: Nakayama, Mizuho, Oshima, Masanobu
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487790/
https://ncbi.nlm.nih.gov/pubmed/30496442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjy075
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