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Treating p53 Mutant Aggregation-Associated Cancer

p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell proliferation and tumor progression. Depending on the p53 mutation, it has been shown to...

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Detaylı Bibliyografya
Yayımlandı:Cancers (Basel)
Yazar: Kanapathipillai, Mathumai
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6025594/
https://ncbi.nlm.nih.gov/pubmed/29789497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10060154
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