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Roles of computational modelling in understanding p53 structure, biology, and its therapeutic targeting

The transcription factor p53 plays pivotal roles in numerous biological processes, including the suppression of tumours. The rich availability of biophysical data aimed at understanding its structure–function relationships since the 1990s has enabled the application of a variety of computational mod...

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Podrobná bibliografie
Vydáno v:J Mol Cell Biol
Hlavní autoři: Tan, Yaw Sing, Mhoumadi, Yasmina, Verma, Chandra S
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487789/
https://ncbi.nlm.nih.gov/pubmed/30726928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjz009
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