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Modulation of Alzheimer’s Aβ protofilament-membrane interactions by lipid headgroups

The molecular pathogenesis of Alzheimer’s disease (AD) is complex and sparsely understood. The relationship between AD’s amyloid β (Aβ) peptides and neuronal membranes is central to Aβ’s cytotoxicity, and is directly modulated by the composition of the lipid headgroups. Molecular studies of the inse...

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Detalhes bibliográficos
Publicado no:ACS Chem Neurosci
Main Authors: Tofoleanu, Florentina, Brooks, Bernard R., Buchete, Nicolae-Viorel
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487634/
https://ncbi.nlm.nih.gov/pubmed/25581460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn500277f
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