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Lipid Headgroups Modulate Membrane Insertion of pHLIP Peptide

The pH low insertion peptide (pHLIP) is an important tool for drug delivery and visualization of acidic tissues produced by various maladies, including cancer, inflammation, and ischemia. Numerous studies indicate that pHLIP exists in three states: unfolded and soluble in water at neutral pH (State...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Kyrychenko, Alexander, Vasquez-Montes, Victor, Ulmschneider, Martin B., Ladokhin, Alexey S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336367/
https://ncbi.nlm.nih.gov/pubmed/25692583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.01.002
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