Amyloid Fibril Design: Limiting Structural Polymorphism in Alzheimer’s Aβ Protofilaments

Nanoscale fibrils formed by amyloid peptides have a polymorphic character, adopting several types of molecular structures in similar growth conditions. This property, evidenced in both experimental (i.e., solid-state NMR) and computational studies, hinders both the structural characterization of Alz...

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Bibliographic Details
Published in:J Phys Chem B
Main Authors: Tywoniuk, Bartlomiej, Yuan, Ye, McCartan, Sarah, Szydłowska, Beata Maria, Tofoleanu, Florentina, Brooks, Bernard, Buchete, Nicolae-Viorel
Format: Artigo
Language:Inglês
Published: 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472267/
https://ncbi.nlm.nih.gov/pubmed/30335383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.8b07423
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