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Amyloid Fibril Design: Limiting Structural Polymorphism in Alzheimer’s Aβ Protofilaments
Nanoscale fibrils formed by amyloid peptides have a polymorphic character, adopting several types of molecular structures in similar growth conditions. This property, evidenced in both experimental (i.e., solid-state NMR) and computational studies, hinders both the structural characterization of Alz...
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| Publicado no: | J Phys Chem B |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6472267/ https://ncbi.nlm.nih.gov/pubmed/30335383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.8b07423 |
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