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Preclinical evaluation of [(18)F]MA3: a CB(2) receptor agonist radiotracer for PET

BACKGROUND AND PURPOSE: Non‐invasive in vivo imaging of cannabinoid CB(2) receptors using PET is pursued to study neuroinflammation. The purpose of this study is to evaluate the in vivo binding specificity of [(18)F]MA3, a CB(2) receptor agonist, in a rat model with local overexpression of human (h)...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Attili, Bala, Celen, Sofie, Ahamed, Muneer, Koole, Michel, Haute, Chris Van Den, Vanduffel, Wim, Bormans, Guy
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487560/
https://ncbi.nlm.nih.gov/pubmed/30588600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14564
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