Evaluation of [(11)C]NMS-E973 as a PET tracer for in vivo visualisation of HSP90

Heat shock protein 90 is an ATP-dependent molecular chaperone important for folding, maturation and clearance of aberrantly expressed proteins and is abundantly expressed (1-2% of all proteins) in the cytosol of all normal cells. In some tumour cells, however, strong expression of HSP90 is also obse...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Vermeulen, Koen, Naus, Evelyne, Ahamed, Muneer, Attili, Bala, Siemons, Maxime, Luyten, Kaat, Celen, Sofie, Schymkowitz, Joost, Rousseau, Frederic, Bormans, Guy
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6376183/
https://ncbi.nlm.nih.gov/pubmed/30809293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.27213
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