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Synthesis, Biodistribution and In vitro Evaluation of Brain Permeable High Affinity Type 2 Cannabinoid Receptor Agonists [(11)C]MA2 and [(18)F]MA3

The type 2 cannabinoid receptor (CB2) is a member of the endocannabinoid system and is known for its important role in (neuro)inflammation. A PET-imaging agent that allows in vivo visualization of CB2 expression may thus allow quantification of neuroinflammation. In this paper, we report the synthes...

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Bibliografski detalji
Izdano u:Front Neurosci
Glavni autori: Ahamed, Muneer, van Veghel, Daisy, Ullmer, Christoph, Van Laere, Koen, Verbruggen, Alfons, Bormans, Guy M.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031696/
https://ncbi.nlm.nih.gov/pubmed/27713686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2016.00431
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