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Micro-flow photosynthesis of new dienophiles for inverse-electron-demand Diels–Alder reactions. Potential applications for pretargeted in vivo PET imaging

Pretargeted PET imaging has emerged as an effective two-step in vivo approach that combines the superior affinity and selectivity of antibodies with the rapid pharmacokinetics and favorable dosimetry of smaller molecules radiolabeled with short-lived radionuclides. This approach can be based on the...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Billaud, Emilie M. F., Shahbazali, Elnaz, Ahamed, Muneer, Cleeren, Frederik, Noël, Timothy, Koole, Michel, Verbruggen, Alfons, Hessel, Volker, Bormans, Guy
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5369547/
https://ncbi.nlm.nih.gov/pubmed/28451267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc02933g
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