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Absence of iron-responsive element-binding protein 2 causes a novel neurodegenerative syndrome
Disruption of cellular iron homeostasis can contribute to neurodegeneration. In mammals, two iron-regulatory proteins (IRPs) shape the expression of the iron metabolism proteome. Targeted deletion of Ireb2 in a mouse model causes profoundly disordered iron metabolism, leading to functional iron defi...
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| Publicado no: | Brain |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6487337/ https://ncbi.nlm.nih.gov/pubmed/30915432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awz072 |
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