Spatially controlled assembly of affinity ligand and enzyme cargo enables targeting ferritin nanocarriers to caveolae

One of the goals of nanomedicine is targeted delivery of therapeutic enzymes to the sub-cellular compartments where their action is needed. Endothelial caveolae-derived endosomes represent an important yet challenging destination for targeting, in part due to smaller size of the entry aperture of ca...

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Publicado en:Biomaterials
Autores principales: Shuvaev, Vladimir V., Khoshnejad, Makan, Pulsipher, Katherine W., Kiseleva, Raisa Yu., Arguiri, Evguenia, Cheung-Lau, Jasmina C., LeFort, Kathleen M., Christofidou-Solomidou, Melpo, Stan, Radu V., Dmochowski, Ivan J., Muzykantov, Vladimir R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487198/
https://ncbi.nlm.nih.gov/pubmed/30273834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2018.09.015
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