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Spatially controlled assembly of affinity ligand and enzyme cargo enables targeting ferritin nanocarriers to caveolae

One of the goals of nanomedicine is targeted delivery of therapeutic enzymes to the sub-cellular compartments where their action is needed. Endothelial caveolae-derived endosomes represent an important yet challenging destination for targeting, in part due to smaller size of the entry aperture of ca...

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Библиографические подробности
Опубликовано в: :Biomaterials
Главные авторы: Shuvaev, Vladimir V., Khoshnejad, Makan, Pulsipher, Katherine W., Kiseleva, Raisa Yu., Arguiri, Evguenia, Cheung-Lau, Jasmina C., LeFort, Kathleen M., Christofidou-Solomidou, Melpo, Stan, Radu V., Dmochowski, Ivan J., Muzykantov, Vladimir R.
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487198/
https://ncbi.nlm.nih.gov/pubmed/30273834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2018.09.015
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