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Anticooperative Binding Governs the Mechanics of Ethidium-Complexed DNA
DNA intercalators bind nucleic acids by stacking between adjacent basepairs. This causes a considerable elongation of the DNA backbone as well as untwisting of the double helix. In the past few years, single-molecule mechanical experiments have become a common tool to characterize these deformations...
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| Veröffentlicht in: | Biophys J |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Biophysical Society
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6486475/ https://ncbi.nlm.nih.gov/pubmed/30954211 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.03.005 |
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