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Studies on the mechanism of DNA cleavage by ethidium.

Ethidium causes the cleavage of DNA via a light and oxygen dependent process. Using covalently closed circular DNA as a substrate, the saturation kinetics and the dependence on superhelical density of the cleavage indicate that intercalated ethidium is mainly responsible for nicking DNA. Superoxide...

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Detalhes bibliográficos
Main Authors: Deniss, I S, Morgan, A R
Formato: Artigo
Idioma:Inglês
Publicado em: 1976
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC342903/
https://ncbi.nlm.nih.gov/pubmed/1257050
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