Organoid single cell profiling identifies a transcriptional signature of glomerular disease

Podocyte injury is central to many forms of kidney disease, but transcriptional signatures reflecting podocyte injury and compensation mechanisms are challenging to analyze in vivo. Human kidney organoids derived from pluripotent stem cells (PSCs), a potentially new model for disease and regeneratio...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:JCI Insight
Autores principales: Harder, Jennifer L., Menon, Rajasree, Otto, Edgar A., Zhou, Jian, Eddy, Sean, Wys, Noel L., O’Connor, Christopher, Luo, Jinghui, Nair, Viji, Cebrian, Cristina, Spence, Jason R., Bitzer, Markus, Troyanskaya, Olga G., Hodgin, Jeffrey B., Wiggins, Roger C., Freedman, Benjamin S., Kretzler, Matthias
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2019
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485369/
https://ncbi.nlm.nih.gov/pubmed/30626756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.122697
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares