Transcriptome analysis of normal-appearing white matter reveals cortisol- and disease-associated gene expression profiles in multiple sclerosis

Inter-individual differences in cortisol production by the hypothalamus–pituitary–adrenal (HPA) axis are thought to contribute to clinical and pathological heterogeneity of multiple sclerosis (MS). At the same time, accumulating evidence indicates that MS pathogenesis may originate in the normal-app...

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Udgivet i:Acta Neuropathol Commun
Main Authors: Melief, Jeroen, Orre, Marie, Bossers, Koen, van Eden, Corbert G., Schuurman, Karianne G., Mason, Matthew R. J., Verhaagen, Joost, Hamann, Jörg, Huitinga, Inge
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485096/
https://ncbi.nlm.nih.gov/pubmed/31023360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0705-7
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