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Enhanced uptake of multiple sclerosis-derived myelin by THP-1 macrophages and primary human microglia
BACKGROUND: The pathological hallmark of multiple sclerosis (MS) is myelin phagocytosis. It remains unclear why microglia and macrophages demyelinate axons in MS, but previously found or yet-unknown changes in the myelin of MS patients could contribute to this process. We therefore studied whether m...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4108133/ https://ncbi.nlm.nih.gov/pubmed/24684721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-11-64 |
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