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Mutant RAS Calms Stressed-Out Cancer Cells
Mutant RAS-driven cancers are infamously resistant to chemotherapeutics. Reporting in Cell, Grabocka and Bar-Sagi (2016) demonstrate that when subjected to stress, mutant KRAS-dependent lipid production leads to upregulated stress granule formation. This confers not only cell-autonomous cytoprotecti...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Dev Cell |
|---|---|
| Prif Awduron: | , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2017
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6484846/ https://ncbi.nlm.nih.gov/pubmed/28118599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2017.01.005 |
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