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Altered NFE2 activity predisposes to leukemic transformation and myelosarcoma with AML-specific aberrations
In acute myeloid leukemia (AML), acquired genetic aberrations carry prognostic implications and guide therapeutic decisions. Clinical algorithms have been improved by the incorporation of novel aberrations. Here, we report the presence and functional characterization of mutations in the transcriptio...
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| Veröffentlicht in: | Blood |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Hematology
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6484461/ https://ncbi.nlm.nih.gov/pubmed/30755419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-09-875047 |
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