A protein quality control pathway regulated by linear ubiquitination

Neurodegenerative diseases are characterized by the accumulation of misfolded proteins in the brain. Insights into protein quality control mechanisms to prevent neuronal dysfunction and cell death are crucial in developing causal therapies. Here, we report that various disease‐associated protein agg...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:EMBO J
Autori principali: van Well, Eva M, Bader, Verian, Patra, Maria, Sánchez‐Vicente, Ana, Meschede, Jens, Furthmann, Nikolas, Schnack, Cathrin, Blusch, Alina, Longworth, Joseph, Petrasch‐Parwez, Elisabeth, Mori, Kohji, Arzberger, Thomas, Trümbach, Dietrich, Angersbach, Lena, Showkat, Cathrin, Sehr, Dominik A, Berlemann, Lena A, Goldmann, Petra, Clement, Albrecht M, Behl, Christian, Woerner, Andreas C, Saft, Carsten, Wurst, Wolfgang, Haass, Christian, Ellrichmann, Gisa, Gold, Ralf, Dittmar, Gunnar, Hipp, Mark S, Hartl, F Ulrich, Tatzelt, Jörg, Winklhofer, Konstanze F
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
Soggetti:
Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484417/
https://ncbi.nlm.nih.gov/pubmed/30886048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018100730
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi