TRAF6 directs FOXP3 localization and facilitates regulatory T‐cell function through K63‐linked ubiquitination

Regulatory T cells (Tregs) are crucial mediators of immune control. The characteristic gene expression and suppressive functions of Tregs depend considerably on the stable expression and activity of the transcription factor FOXP3. Transcriptional regulation of the Foxp3 gene has been studied in dept...

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Dades bibliogràfiques
Publicat a:EMBO J
Autors principals: Ni, Xuhao, Kou, Wei, Gu, Jian, Wei, Ping, Wu, Xiao, Peng, Hao, Tao, Jinhui, Yan, Wei, Yang, Xiaoping, Lebid, Andriana, Park, Benjamin V, Chen, Zuojia, Tian, Yizhu, Fu, Juan, Newman, Stephanie, Wang, Xiaoming, Shen, Hongbin, Li, Bin, Blazar, Bruce R., Wang, Xuehao, Barbi, Joseph, Pan, Fan, Lu, Ling
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484404/
https://ncbi.nlm.nih.gov/pubmed/30886050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201899766
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