Cancer-associated fibroblasts enhance the chemoresistance of CD73(+) hepatocellular carcinoma cancer cells via HGF-Met-ERK1/2 pathway

BACKGROUND: Cancer-associated fibroblasts (CAFs) are a major component of hepatocellular carcinoma (HCC) stroma that are critically involved in HCC cancer chemoresistance, but the mechanism has not been elucidated. Previous studies have reported CD73 exerted an immunosuppressive function in cancer....

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Detalhes bibliográficos
Publicado no:Ann Transl Med
Main Authors: Peng, Hao, Xue, Rong, Ju, Zheng, Qiu, Jiannan, Wang, Jiawei, Yan, Wei, Gan, Xiaojie, Tian, Yizhu, Shen, Hongbin, Wang, Xiaoming, Wang, Xuehao, Ni, Xuhao, Yu, Yue, Lu, Ling
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7396767/
https://ncbi.nlm.nih.gov/pubmed/32793700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm-20-1038
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