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Voltage-dependent activation in EAG channels follows a ligand-receptor rather than a mechanical-lever mechanism
Ether-a-go-go family (EAG) channels play a major role in many physiological processes in humans, including cardiac repolarization and cell proliferation. Cryo-EM structures of two of them, K(V)10.1 and human ether-a-go-go-related gene (hERG or K(V)11.1), have revealed an original nondomain-swapped s...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6484144/ https://ncbi.nlm.nih.gov/pubmed/30808709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007626 |
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