Cross-talk between N-terminal and C-terminal domains in stromal interaction molecule 2 (STIM2) determines enhanced STIM2 sensitivity

Store-operated Ca(2+) entry (SOCE) is a ubiquitous pathway for Ca(2+) influx across the plasma membrane (PM). SOCE is mediated by the endoplasmic reticulum (ER)-associated Ca(2+)-sensing proteins stromal interaction molecule 1 (STIM1) and STIM2, which transition into an active conformation in respon...

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Udgivet i:J Biol Chem
Main Authors: Emrich, Scott M., Yoast, Ryan E., Xin, Ping, Zhang, Xuexin, Pathak, Trayambak, Nwokonko, Robert, Gueguinou, Maxime F., Subedi, Krishna P., Zhou, Yandong, Ambudkar, Indu S., Hempel, Nadine, Machaca, Khaled, Gill, Donald L., Trebak, Mohamed
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2019
Fag:
Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484143/
https://ncbi.nlm.nih.gov/pubmed/30824535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006801
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