L-type Ca(2+) channel blockers promote vascular remodeling through activation of STIM proteins

Voltage-gated L-type Ca(2+) channel (Ca(v)1.2) blockers (LCCBs) are major drugs for treating hypertension, the preeminent risk factor for heart failure. Vascular smooth muscle cell (VSMC) remodeling is a pathological hallmark of chronic hypertension. VSMC remodeling is characterized by molecular rew...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Johnson, Martin T., Gudlur, Aparna, Zhang, Xuexin, Xin, Ping, Emrich, Scott M., Yoast, Ryan E., Courjaret, Raphael, Nwokonko, Robert M., Li, Wei, Hempel, Nadine, Machaca, Khaled, Gill, Donald L., Hogan, Patrick G., Trebak, Mohamed
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7382247/
https://ncbi.nlm.nih.gov/pubmed/32641503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2007598117
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados