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The native ORAI channel trio underlies the diversity of Ca(2+) signaling events

The essential role of ORAI1 channels in receptor-evoked Ca(2+) signaling is well understood, yet little is known about the physiological activation of the ORAI channel trio natively expressed in all cells. The roles of ORAI2 and ORAI3 have remained obscure. We show that ORAI2 and ORAI3 channels play...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Yoast, Ryan E., Emrich, Scott M., Zhang, Xuexin, Xin, Ping, Johnson, Martin T., Fike, Adam J., Walter, Vonn, Hempel, Nadine, Yule, David I., Sneyd, James, Gill, Donald L., Trebak, Mohamed
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229178/
https://ncbi.nlm.nih.gov/pubmed/32415068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16232-6
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