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The native ORAI channel trio underlies the diversity of Ca(2+) signaling events

The essential role of ORAI1 channels in receptor-evoked Ca(2+) signaling is well understood, yet little is known about the physiological activation of the ORAI channel trio natively expressed in all cells. The roles of ORAI2 and ORAI3 have remained obscure. We show that ORAI2 and ORAI3 channels play...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Yoast, Ryan E., Emrich, Scott M., Zhang, Xuexin, Xin, Ping, Johnson, Martin T., Fike, Adam J., Walter, Vonn, Hempel, Nadine, Yule, David I., Sneyd, James, Gill, Donald L., Trebak, Mohamed
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229178/
https://ncbi.nlm.nih.gov/pubmed/32415068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16232-6
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